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Did you know that most of the symptoms unobserved on the skin are the very first clues that you might have skin cancer? But in most of the cases, skin cancer is clearly visible outside the body. It is easy to spot a mole, a rash, a blemish or a lesion. But sometime exceptions can arise. This occurs when the symptoms are not seen on the skin. In the case of advanced melanoma, the symptoms include pain, headache and other symptoms not observed on the skin.